英国上市公司365

杜仲叶提取物对断奶仔猪生长性能、抗氧化能力和肠道功能的影响

Effects of Eucommia ulmoides leaf extracts on growth performance, antioxidant capacity and intestinal function in weaned piglets

作者：Haoxuan Ding ;Aizhi Cao ;Haiyun Li;Yang Zhao;Jie Feng.

发表期刊：Animal Physiology and Animal Nutrition. 2020 Jul;104(4):1169-1177.

杜仲是一种传统的中药,具有多种潜在的生物活性,如抗炎、抗氧化和免疫调节活性。本研究旨在确定杜仲叶提取物(ELE)在饮食中的作用,对断奶仔猪的生长性能、抗氧化能力和肠道功能的影响。200 只杂交仔猪(杜洛克×长白×约克夏),平均初始体重12.96 ± 0.28 kg,被随机分配到5个处理组:C0(基础饲粮)、C1(基础饲粮+抗生素),以及在基础饲粮中添加不同水平的ELE(0.2、0.3或0.4 g/kg饲粮)。结果显示,ELE或抗生素补充明显降低了腹泻率,而0.3 g/kg ELE增加了平均日增重(p<0.05)。0.3 g/kg ELE增加了血清和肝脏的碱性磷酸酶(AKP)水平和总抗氧化能力(T-AOC),以及血清白蛋白和总蛋白(TP)含量(p<0.05)。饲喂0.3 g/kg ELE的饲粮,十二指肠内容物的脂肪酶活性和空肠内容物的胰蛋白酶活性均有改善(p<0.05)。0.3 g/kg ELE处理组的十二指肠和空肠绒毛高度明显高于C0组(p<0.05)。这些结果表明,杜仲叶提取物补充对断奶仔猪的抗氧化能力和肠道功能有益影响,同时也可提高生长性能和降低腹泻率。因此,杜仲叶提取物可作为抗生素的潜在替代品。

Eucommia ulmoides is traditional Chinese medicine, and it possesses several potential bioactivities,suchasanti-inflammatory,antioxidantandimmuneregulatoryactivities. This study was conducted to determine the effects of dietary Eucommia ulmoides leaf extracts (ELE) on growth performance, antioxidant capacity and intestinal function of weaned piglets. Two hundred crossbred (Duroc×Landrace×Yorkshire) piglets with an average initial weight of 12.96±0.28kg were randomly allotted to five treat-ments: C0 (basal diet), C1 (basal diet+antibiotics) and basal diet supplemented with increasing levels of ELE (0.2, 0.3 or 0.4g/kg of feed). The results showed that ELE or antibiotics supplementation remarkably decreased diarrhoea rate and 0.3g/kg ELE increased average daily gain compared with C0 (p<.05). 0.3g/kg ELE increased alkaline phosphatase (AKP) levels and total antioxidant capacity (T-AOC) in serum and liver, as well as increased the content of serum albumin and total protein (TP) compared with the C0 (p<.05). The lipase activity of duodenum content and trypsin activity of jejunum content were improved fed diets containing 0.3g/kg ELE com-pared with C0 (p<.05). The 0.3g/kg ELE treatments have a higher villus height of the duodenum and jejunum compared with the C0 (p<.05). These results suggested that ELE supplementation had beneficial effects on antioxidant and intestinal function in weaned piglets, which also could increase growth performance and decreased diar-rhoea rate. Accordingly, ELE is a potential alternative to antibiotics.

获取原文